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Ceruloplasmin alters intracellular iron regulated proteins and pathways: Ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1α

Ceruloplasmin (Cp) is a ferroxidase important to the regulation of both systemic and intracellular iron levels. Cp has a critical role in iron metabolism in the brain and retina as shown in patients with aceruloplasminemia and in Cp−/−hep−/y mice where iron accumulates and neural and retinal degener...

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Detalhes bibliográficos
Main Authors: Harned, J., Ferrell, J., Nagar, S., Goralska, M., Fleisher, L.N., McGahan, M.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535017/
https://ncbi.nlm.nih.gov/pubmed/22343016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.02.001
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