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Face selective reduction of the exocyclic double bond in isatin derived spirocyclic lactones
We report an unusual face selective reduction of the exocyclic double bond in the α-methylene-γ-butyrolactone motif of spiro-oxindole systems. The spiro-oxindoles were assembled by an indium metal mediated Barbier-type reaction followed by an acid catalyzed lactonization.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535013/ https://ncbi.nlm.nih.gov/pubmed/23160888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob27008k |
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