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Mutation of crp mediates Serratia marcescens serralysin and global secreted protein production

The bacterial species Serratia marcescens secretes both beneficial and cytotoxic proteins. Here we report that a crp mutant exhibited elevated secreted protease activity. A genetic screen revealed that the gene coding for the metalloprotease serralysin was necessary for the elevated proteolysis, and...

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Main Authors: Shanks, Robert M.Q., Stella, Nicholas A., Arena, Kristin E., Fender, James E.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534799/
https://ncbi.nlm.nih.gov/pubmed/23072819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resmic.2012.10.006
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