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Phytol/Phytanic Acid and Insulin Resistance: Potential Role of Phytanic Acid Proven by Docking Simulation and Modulation of Biochemical Alterations

Since activation of PPARγ is the main target for the antidiabetic effect of TZDs, especially when it heterodimerizes with RXR, we aimed to test the potential antidiabetic effect of phytol (250 mg/kg), the natural precursor of phytanic acid, a RXR ligand and/or pioglitazone (5 mg/kg) to diabetic insu...

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Detaylı Bibliyografya
Asıl Yazarlar: Elmazar, Mohamed M., El-Abhar, Hanan S., Schaalan, Mona F., Farag, Nahla A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534692/
https://ncbi.nlm.nih.gov/pubmed/23300941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045638
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