A Polymeric Nanomedicine Diminishes Inflammatory Events in Renal Tubular Cells

The polyglutamic acid/peptoid 1 (QM56) nanoconjugate inhibits apoptosis by interfering with Apaf-1 binding to procaspase-9. We now describe anti-inflammatory properties of QM56 in mouse kidney and renal cell models. In cultured murine tubular cells, QM56 inhibited the inflammatory response to Tweak,...

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Detalhes bibliográficos
Main Authors: Ucero, Álvaro C., Berzal, Sergio, Ocaña-Salceda, Carlos, Sancho, Mónica, Orzáez, Mar, Messeguer, Angel, Ruiz-Ortega, Marta, Egido, Jesús, Vicent, María J., Ortiz, Alberto, Ramos, Adrián M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534689/
https://ncbi.nlm.nih.gov/pubmed/23300960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051992
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