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Old Players with a Newly Defined Function: Fra-1 and c-Fos Support Growth of Human Malignant Breast Tumors by Activating Membrane Biogenesis at the Cytoplasm

A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells demand high rates of phospholipid synthesis required for membrane biogenesis to support their growth. c-Fos, in addition to its AP-1 transcription factor activity, is the only protein known up to date that...

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Библиографические подробности
Главные авторы: Motrich, Ruben D., Castro, Gonzalo M., Caputto, Beatriz L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534677/
https://ncbi.nlm.nih.gov/pubmed/23301044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053211
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