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Expansion of Activated Memory CD4(+) T Cells Affects Infectivity of CCR5-Tropic HIV-1 in Humanized NOD/SCID/JAK3(null) Mice

Humanized mice reconstituted with human hematopoietic cells have been developed as an experimental animal model for human immunodeficiency virus type 1 (HIV-1) infection. Myeloablative irradiation is usually performed to augment the engraftment of donor hematopoietic stem cells (HSCs) in recipient m...

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Detalhes bibliográficos
Main Authors: Terahara, Kazutaka, Ishige, Masayuki, Ikeno, Shota, Mitsuki, Yu-ya, Okada, Seiji, Kobayashi, Kazuo, Tsunetsugu-Yokota, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534664/
https://ncbi.nlm.nih.gov/pubmed/23301078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053495
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