Ubiquitin initiates sorting of Golgi and plasma membrane proteins into the vacuolar degradation pathway

BACKGROUND: In yeast and mammals, many plasma membrane (PM) proteins destined for degradation are tagged with ubiquitin. These ubiquitinated proteins are internalized into clathrin-coated vesicles and are transported to early endosomal compartments. There, ubiquitinated proteins are sorted by the en...

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Bibliographic Details
Main Authors: Scheuring, David, Künzl, Fabian, Viotti, Corrado, Yan, Melody San Wan, Jiang, Liwen, Schellmann, Swen, Robinson, David G, Pimpl, Peter
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534617/
https://ncbi.nlm.nih.gov/pubmed/22970698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2229-12-164
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