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Ubiquitin initiates sorting of Golgi and plasma membrane proteins into the vacuolar degradation pathway
BACKGROUND: In yeast and mammals, many plasma membrane (PM) proteins destined for degradation are tagged with ubiquitin. These ubiquitinated proteins are internalized into clathrin-coated vesicles and are transported to early endosomal compartments. There, ubiquitinated proteins are sorted by the en...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534617/ https://ncbi.nlm.nih.gov/pubmed/22970698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2229-12-164 |
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