4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages

Obesity-induced adipose inflammation is characterized by recruitment of macrophages to adipose tissue and release of inflammatory cytokines. 4-1BB, a costimulatory receptor, modulates inflammatory processes through interaction with its ligand 4-1BBL on immune cell surfaces. In this study, we examine...

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Main Authors: Tu, Thai Hien, Kim, Chu-Sook, Goto, Tsuyoshi, Kawada, Teruo, Kim, Byung-Sam, Yu, Rina
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534384/
https://ncbi.nlm.nih.gov/pubmed/23316108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/972629
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