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4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

The cell envelope of Mycobacterium tuberculosis, the causative agent of tuberculosis in humans, contains lipids with unusual structures. These lipids play a key role in both virulence and resistance to the various hostile environments encountered by the bacteria during infection. They are synthesize...

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Detalhes bibliográficos
Main Authors: Leblanc, Cécile, Prudhomme, Thomas, Tabouret, Guillaume, Ray, Aurélie, Burbaud, Sophie, Cabantous, Stéphanie, Mourey, Lionel, Guilhot, Christophe, Chalut, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534377/
https://ncbi.nlm.nih.gov/pubmed/23308068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003097
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