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ERα mediates alcohol-induced deregulation of Pol III genes in breast cancer cells

The association of alcohol consumption and breast cancer is more pronounced in cases that are positive for estrogen receptor (ER+) than in cases that are negative (ER−). Its mechanism remains to be determined. Deregulation of RNA polymerase III (Pol III) transcription enhances cellular tRNAs and 5S...

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Autori principali: Zhang, Qingsong, Jin, Jian, Zhong, Qian, Yu, Xiaoli, Levy, Daniel, Zhong, Shuping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534194/
https://ncbi.nlm.nih.gov/pubmed/23054611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs316
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