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β(1)-Adrenoceptor Autoantibodies from DCM Patients Enhance the Proliferation of T Lymphocytes through the β(1)-AR/cAMP/PKA and p38 MAPK Pathways

BACKGROUND: Autoantibodies against the second extracellular loop of the β(1)-adrenergic receptor (β(1)-AA) not only contribute to increased susceptibility to heart failure, but also play a causative role in myocardial remodeling through their sympathomimetic-like effects that are induced upon bindin...

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Autors principals: Du, Yunhui, Yan, Li, Wang, Jin, Zhan, Wenzhang, Song, Kai, Han, Xue, Li, Xiao, Cao, Jimin, Liu, Huirong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534136/
https://ncbi.nlm.nih.gov/pubmed/23300817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052911
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