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Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB

Ovarian cancer, one of inflammation-associated cancers, is the fifth leading cause of cancer deaths among women. Inflammation in the tumor microenvironment is associated with peritoneal tumor dissemination and massive ascites, which contribute to high mortality in ovarian cancer. Tumor suppressor p5...

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Huvudupphovsmän: Son, Deok-Soo, Kabir, Syder M., Dong, Yuan-Lin, Lee, Eunsook, Adunyah, Samuel E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534106/
https://ncbi.nlm.nih.gov/pubmed/23300534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051116
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