An efficient RNA interference screening strategy for gene functional analysis

BACKGROUND: RNA interference (RNAi) is commonly applied in genome-scale gene functional screens. However, a one-on-one RNAi analysis that targets each gene is cost-ineffective and laborious. Previous studies have indicated that siRNAs can also affect RNAs that are near-perfectly complementary, and t...

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Autori principali: Chang, Chih-Hung, Wang, Hsiang-Iu, Lu, Hsiang-Chia, Chen, Cheng-En, Chen, Hong-Hwa, Yeh, Hsin-Hung, Tang, Chuan Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Methodology Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533828/
https://ncbi.nlm.nih.gov/pubmed/22988976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-491
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