Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator

BACKGROUND: More than 50% of patients undergoing lifelong suppressive antiviral treatment for HIV-1 infection develop minor HIV-1-associated neurocognitive disorders. Neurological complications during HIV-1 infection are the result of direct neuronal damage by proinflammatory products released from...

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Hlavní autoři: Mehla, Rajeev, Bivalkar-Mehla, Shalmali, Nagarkatti, Mitzi, Chauhan, Ashok
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533742/
https://ncbi.nlm.nih.gov/pubmed/23078780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-239
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