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Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome
The 8p11 myeloproliferative syndrome is a rare, aggressive myeloproliferative neoplasm characterized by constitutively active FGFR1 fusion proteins that arise from specific chromosomal translocations and which drive aberrant proliferation. Although FGFR1 inhibitors have shown in vitro activity again...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533670/ https://ncbi.nlm.nih.gov/pubmed/22875613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.066407 |
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