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Absence of the RET+3:T allele in the MTC patients
The mutations of the RET proto-oncogene contributes to the development of MTC by increasing the activity of the receptor encoded by this gene. Variant T of polymorphism rs2435357 located in the enhancer of the RET gene reduces the enhancer’s activity. The opposite effects of rs2435357 and the mutati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533580/ https://ncbi.nlm.nih.gov/pubmed/23088776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-10-14 |
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