HIV-1 infection–induced apoptotic microparticles inhibit human DCs via CD44

Acute HIV-1 infection results in dysregulated immunity, which contributes to poor control of viral infection. DCs are key regulators of both adaptive and innate immune responses needed for controlling HIV-1, and we surmised that factors elicited during acute HIV-1 infection might impede DC function....

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Hauptverfasser: Frleta, Davor, Ochoa, Carolyn E., Kramer, Holger B., Khan, Shaukat Ali, Stacey, Andrea R., Borrow, Persephone, Kessler, Benedikt M., Haynes, Barton F., Bhardwaj, Nina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533550/
https://ncbi.nlm.nih.gov/pubmed/23160198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64439
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