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Intravaginal immunization with HPV vectors induces tissue-resident CD8(+) T cell responses

The induction of persistent intraepithelial CD8(+) T cell responses may be key to the development of vaccines against mucosally transmitted pathogens, particularly for sexually transmitted diseases. Here we investigated CD8(+) T cell responses in the female mouse cervicovaginal mucosa after intravag...

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Detalhes bibliográficos
Main Authors: Çuburu, Nicolas, Graham, Barney S., Buck, Christopher B., Kines, Rhonda C., Pang, Yuk-Ying S., Day, Patricia M., Lowy, Douglas R., Schiller, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533540/
https://ncbi.nlm.nih.gov/pubmed/23143305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63287
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