The SH2-domain-containing inositol 5-phosphatase (SHIP) limits the motility of neutrophils and their recruitment to wounds in zebrafish

Neutrophil recruitment to sites of injury or infection is essential for host defense, but it needs to be tightly regulated to prevent tissue damage. Phosphoinositide 3-kinase (PI3K), which generates the phosphatidylinositol (3,4,5)-trisphosphate [PI(3,4,5)P(3)], is necessary for neutrophil motility...

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Bibliographic Details
Main Authors: Lam, Pui-ying, Yoo, Sa Kan, Green, Julie M., Huttenlocher, Anna
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2012
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533387/
https://ncbi.nlm.nih.gov/pubmed/22946052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.106625
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