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From an ACE polymorphism to genome-wide searches for eQTL
Angiotensin I–converting enzyme (ACE, or DCP1) is a zinc metallopeptidase that converts angiotensin I into the vasoactive and aldosterone-stimulating peptide angiotensin II and cleaves bradykinin into inactive peptides. Plasma ACE measurement is widely used for the diagnosis of sarcoidosis. While en...
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| Format: | Artigo |
| Jezik: | Inglês |
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American Society for Clinical Investigation
2013
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533308/ https://ncbi.nlm.nih.gov/pubmed/23281417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66618 |
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