p62 Links β-adrenergic input to mitochondrial function and thermogenesis

The scaffold protein p62 (sequestosome 1; SQSTM1) is an emerging key molecular link among the metabolic, immune, and proliferative processes of the cell. Here, we report that adipocyte-specific, but not CNS-, liver-, muscle-, or myeloid-specific p62-deficient mice are obese and exhibit a decreased m...

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Detalhes bibliográficos
Main Authors: Müller, Timo D., Lee, Sang Jun, Jastroch, Martin, Kabra, Dhiraj, Stemmer, Kerstin, Aichler, Michaela, Abplanalp, Bill, Ananthakrishnan, Gayathri, Bhardwaj, Nakul, Collins, Sheila, Divanovic, Senad, Endele, Max, Finan, Brian, Gao, Yuanqing, Habegger, Kirk M., Hembree, Jazzmin, Heppner, Kristy M., Hofmann, Susanna, Holland, Jenna, Küchler, Daniela, Kutschke, Maria, Krishna, Radha, Lehti, Maarit, Oelkrug, Rebecca, Ottaway, Nickki, Perez-Tilve, Diego, Raver, Christine, Walch, Axel K., Schriever, Sonja C., Speakman, John, Tseng, Yu-Hua, Diaz-Meco, Maria, Pfluger, Paul T., Moscat, Jorge, Tschöp, Matthias H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533288/
https://ncbi.nlm.nih.gov/pubmed/23257354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64209
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