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Induced pluripotent stem cell–derived cardiomyocytes in studies of inherited arrhythmias

The discovery of the genetic basis of inherited arrhythmias has paved the way for an improved understanding of arrhythmogenesis in a wide spectrum of life-threatening conditions. In vitro expression of mutations and transgenic animal models have been instrumental in enhancing this understanding, but...

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Détails bibliographiques
Auteurs principaux: Priori, Silvia G., Napolitano, Carlo, Di Pasquale, Elisa, Condorelli, Gianluigi
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533271/
https://ncbi.nlm.nih.gov/pubmed/23281414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62838
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