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Structure Dependence of Long-Chain [(18)F]Fluorothia Fatty Acids as Myocardial Fatty Acid Oxidation Probes

In-vivo imaging of regional fatty acid oxidation (FAO) rates would have considerable potential for evaluation of mammalian diseases. We have synthe sized and evaluated (18)F-labeled thia fatty acid analogues as metabolically trapped FAO probes to understand the effect of chain length, degree of unsa...

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Autors principals: Pandey, Mukesh K., Belanger, Anthony P., Wang, Shuyan, DeGrado, Timothy R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533245/
https://ncbi.nlm.nih.gov/pubmed/23153307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301345v
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