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Regulation of the tumor suppressor PML by sequential post-translational modifications

Post-translational modifications (PTMs) regulate multiple biological functions of the promyelocytic leukemia (PML) protein and also the fission, disassembly, and rebuilding of PML nuclear bodies (PML-NBs) during the cell cycle. Pathway-specific PML modification patterns ensure proper signal output f...

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Detalhes bibliográficos
Main Authors: Schmitz, M. Lienhard, Grishina, Inna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533183/
https://ncbi.nlm.nih.gov/pubmed/23293771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00204
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