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Stress-induced mutation via DNA breaks in Escherichia coli: A molecular mechanism with implications for evolution and medicine

Evolutionary theory assumed that mutations occur constantly, gradually, and randomly over time. This formulation from the “modern synthesis” of the 1930s was embraced decades before molecular understanding of genes or mutations. Since then, our labs and others have elucidated mutation mechanisms act...

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Autors principals: Rosenberg, Susan M, Shee, Chandan, Frisch, Ryan L, Hastings, P J
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533179/
https://ncbi.nlm.nih.gov/pubmed/22911060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200050
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