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Cholinergic modulation during acquisition of olfactory fear conditioning alters learning and stimulus generalization in mice

We investigated the role of cholinergic neurotransmission in olfactory fear learning. Mice receiving pairings of odor and foot shock displayed fear to the trained odor the following day. Pretraining injections of the nicotinic antagonist mecamylamine had no effect on subsequent freezing, while the m...

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Détails bibliographiques
Auteurs principaux: Pavesi, Eloisa, Gooch, Allison, Lee, Elizabeth, Fletcher, Max L.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533131/
https://ncbi.nlm.nih.gov/pubmed/23242418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.028324.112
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