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The ticking tail: daily oscillations in mRNA poly(A) tail length drive circadian cycles in protein synthesis

In this issue of Genes & Development, Kojima and colleagues (pp. 2724–2736) examined the impact of mRNA poly(A) tail length on circadian gene expression. Their study demonstrates how dynamic changes in transcript poly(A) tail length can lead to rhythmic protein expression, irrespective of whethe...

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Hlavní autoři: Gotic, Ivana, Schibler, Ueli
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533071/
https://ncbi.nlm.nih.gov/pubmed/23249731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.210690.112
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