Genetic Predictors of Taxane-induced Neurotoxicity in a SWOG Phase III Intergroup Adjuvant Breast Cancer Treatment Trial (S0221)

PURPOSE: We assessed SNPS in the Fanconi Anemia (FA)/BRCA pathway in women being was taxanes for breast cancer in an effort to find a prognostic biomarker for neurological toxicities, which while improve survival remain a debilitating outcome. PATIENTS AND METHODS: We used data and samples (n=888) f...

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Autori principali: Sucheston, Lara E., Zhao, Hua, Yao, Song, Zirpoli, Gary, Liu, Song, Barlow, William E., Budd, G. Thomas, Hershman, Dawn L., Davis, Warren, Ciupak, Gregory L., Stewart, James A., Isaacs, Claudine, Hobday, Timothy J., Salim, Muhammad, Hortobagyi, Gabriel N., Gralow, Julie R., Livingston, Robert B., Albain, Kathy S., Hayes, Daniel F., Ambrosone, Christine B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532924/
https://ncbi.nlm.nih.gov/pubmed/21766209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1671-3
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