Hepatic microtubule acetylation and stability induced by chronic alcohol exposure impair nuclear translocation of STAT3 and STAT5B, but not Smad2/3

Although alcoholic liver disease is clinically well described, the molecular basis for alcohol-induced hepatotoxicity is not well understood. Previously, we found that alcohol exposure led to increased microtubule acetylation and stability in polarized, hepatic WIF-B cells and in livers from ethanol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fernandez, David J., Tuma, Dean J., Tuma, Pamela L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2012
Gaiak:
Liver and Biliary Tract
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532545/
https://ncbi.nlm.nih.gov/pubmed/23064763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00071.2012
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak