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Glycolysis Inhibitor Screening Identifies the Bis-geranylacylphloroglucinol Protonophore Moronone from Moronobea coccinea

Tumor cells exhibit enhanced glucose consumption and lactate production even when supplied with adequate oxygen (a phenomenon known as the Warburg effect, or aerobic glycolysis). Pharmacological inhibition of aerobic glycolysis represents a potential tumor-selective approach that targets the metabol...

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Bibliografiska uppgifter
Huvudupphovsmän: Datta, Sandipan, Li, Jun, Mahdi, Fakhri, Jekabsons, Mika B., Nagle, Dale G., Zhou, Yu-Dong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532528/
https://ncbi.nlm.nih.gov/pubmed/23245650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np300711e
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