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No Evidence for a Functional Role of Bi-Directional Notch Signaling during Angiogenesis

The Delta-Notch pathway is a signal exchanger between adjacent cells to regulate numerous differentiation steps during embryonic development. Blood vessel formation by sprouting angiogenesis requires high expression of the Notch ligand DLL4 in the leading tip cell, while Notch receptors in the trail...

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Detalhes bibliográficos
Main Authors: Liebler, Sven S., Feldner, Anja, Adam, M. Gordian, Korff, Thomas, Augustin, Hellmut G., Fischer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532505/
https://ncbi.nlm.nih.gov/pubmed/23300864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053074
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