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Role of Actin Dependent Nuclear Deformation in Regulating Early Gene Expression

The nucleus of a living cell is constantly undergoing changes in shape and size as a result of various mechanical forces in physiology. These changes correlate with alterations in gene expression, however it is unclear whether nuclear deformation alone is sufficient to elicit these alterations. We u...

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Detalhes bibliográficos
Main Authors: Gupta, Soumya, Marcel, Nimi, Sarin, Apurva, Shivashankar, G. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532443/
https://ncbi.nlm.nih.gov/pubmed/23285252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053031
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