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Protective Effect of Tropisetron on Rodent Hepatic Injury after Trauma-Hemorrhagic Shock through P38 MAPK-Dependent Hemeoxygenase-1 Expression

Tropisetron can decrease inflammatory cell responses and alleviate organ damage caused by trauma-hemorrhage, but the mechanism of these effects remains unknown. The p38 mitogen-activated protein kinase/hemeoxygenase-1 (p38 MAPK/HO-1) pathway exerts anti-inflammatory effects on different tissues. The...

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Bibliografiske detaljer
Main Authors: Liu, Fu-Chao, Yu, Huang-Ping, Hwang, Tsong-Long, Tsai, Yung-Fong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532400/
https://ncbi.nlm.nih.gov/pubmed/23285267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053203
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