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A combination of intradermal jet-injection and electroporation overcomes in vivo dose restriction of DNA vaccines
BACKGROUND: The use of optimized delivery devices has been shown to enhance the potency of DNA vaccines. However, further optimization of DNA vaccine delivery is needed for this vaccine modality to ultimately be efficacious in humans. METHODS: Herein we evaluated antigen expression and immunogenicit...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532290/ https://ncbi.nlm.nih.gov/pubmed/22873174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-10-5 |
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