Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis

BACKGROUND: Human T-cell Leukemia Virus type 1 (HTLV-1) infects 20 million individuals world-wide and causes Adult T-cell Leukemia/Lymphoma (ATLL), a highly aggressive T-cell cancer. ATLL is refractory to treatment with conventional chemotherapy and fewer than 10% of afflicted individuals survive mo...

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Hlavní autoři: Zane, Linda, Yasunaga, Junichiro, Mitagami, Yu, Yedavalli, Venkat, Tang, Sai-Wen, Chen, Chia-Yen, Ratner, Lee, Lu, Xiongbin, Jeang, Kuan-Teh
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532233/
https://ncbi.nlm.nih.gov/pubmed/23256545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-114
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