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Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation

BACKGROUND: Imaging studies have demonstrated that ventilation during bronchoconstriction in subjects with asthma is patchy with large ventilation defective areas (Vdefs). Based on a theoretical model, we postulated that during bronchoconstriction, as smooth muscle force activation increases, a patc...

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Detalhes bibliográficos
Main Authors: Harris, R. Scott, Fujii-Rios, Hanae, Winkler, Tilo, Musch, Guido, Vidal Melo, Marcos F., Venegas, José G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532117/
https://ncbi.nlm.nih.gov/pubmed/23285270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053216
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