Multiple NF-κB Sites in HIV-1 Subtype C Long Terminal Repeat Confer Superior Magnitude of Transcription and Thereby the Enhanced Viral Predominance

We demonstrate that at least three different promoter variant strains of HIV-1 subtype C have been gradually expanding and replacing the standard subtype C viruses in India, and possibly in South Africa and other global regions, over the past decade. The new viral strains contain an additional NF-κB...

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Hauptverfasser: Bachu, Mahesh, Yalla, Swarupa, Asokan, Mangaiarkarasi, Verma, Anjali, Neogi, Ujjwal, Sharma, Shilpee, Murali, Rajesh V., Mukthey, Anil Babu, Bhatt, Raghavendra, Chatterjee, Snehajyoti, Rajan, Roshan Elizabeth, Cheedarla, Narayana, Yadavalli, Venkat S., Mahadevan, Anita, Shankar, Susarla K., Rajagopalan, Nirmala, Shet, Anita, Saravanan, Shanmugam, Balakrishnan, Pachamuthu, Solomon, Suniti, Vajpayee, Madhu, Satish, Kadappa Shivappa, Kundu, Tapas K., Jeang, Kuan-Teh, Ranga, Udaykumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531786/
https://ncbi.nlm.nih.gov/pubmed/23132857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397158
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