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In Vitro Evaluation of ESE-15-ol, an Estradiol Analogue with Nanomolar Antimitotic and Carbonic Anhydrase Inhibitory Activity

Antimitotic compounds are still one of the most widely used chemotherapeutic anticancer drugs in the clinic today. Given their effectiveness against cancer it is beneficial to continue enhancing these drugs. One way is to improve the bioavailability and efficacy by synthesizing derivatives that reve...

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Bibliografiske detaljer
Main Authors: Stander, Barend Andre, Joubert, Fourie, Tu, Chingkuang, Sippel, Katherine H., McKenna, Robert, Joubert, Annie Margaretha
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531393/
https://ncbi.nlm.nih.gov/pubmed/23300615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052205
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