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The Role of Insulin C-Peptide in the Coevolution Analyses of the Insulin Signaling Pathway: A Hint for Its Functions

As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive...

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Detalhes bibliográficos
Main Authors: Wang, Shuai, Wei, Wei, Zheng, Yadong, Hou, Junling, Dou, Yongxi, Zhang, Shaohua, Luo, Xuenong, Cai, Xuepeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531361/
https://ncbi.nlm.nih.gov/pubmed/23300796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052847
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