Interplay between Basic Residues of Hepatitis C Virus Glycoprotein E2 with Viral Receptors, Neutralizing Antibodies and Lipoproteins

Positively-charged amino acids are located at specific positions in the envelope glycoprotein E2 of the hepatitis C virus (HCV): two histidines (H) and four arginines (R) in two conserved WHY and one RGERCDLEDRDR motifs, respectively. Additionally, the E2 hypervariable region 1 (HVR1) is rich in bas...

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Bibliographic Details
Main Authors: Koutsoudakis, George, Dragun, Jakub, Pérez-del-Pulgar, Sofia, Coto-Llerena, Mairene, Mensa, Laura, Crespo, Gonzalo, González, Patricia, Navasa, Miquel, Forns, Xavier
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531341/
https://ncbi.nlm.nih.gov/pubmed/23300734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052651
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