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Longitudinal diffusion tensor imaging in amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, caused by progressive loss of motor neurons. Changes are widespread in the subcortical white matter in ALS. Diffusion tensor imaging (DTI) detects pathological changes in white matter fibres in vivo, based on alte...

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Bibliographic Details
Main Authors: Keil, Carsten, Prell, Tino, Peschel, Thomas, Hartung, Viktor, Dengler, Reinhard, Grosskreutz, Julian
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531302/
https://ncbi.nlm.nih.gov/pubmed/23134591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-141
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