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Poliovirus Polyuridylic Acid Polymerase and RNA Replicase Have the Same Viral Polypeptide

A poliovirus-specific polyuridylic acid [poly(U)] polymerase that copies a polyadenylic acid template complexed to an oligouridylic acid primer was isolated from the membrane fraction of infected HeLa cells and was found to sediment at 4 to 5S on a linear 5 to 20% glycerol gradient. When the poly(U)...

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Bibliographic Details
Published in:J Virol
Main Authors: Flanegan, James B., Baltimore, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1979
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/219230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.29.1.352-360.1979
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