Selection of an Antibiotic-Hypersusceptible Mutant of Pseudomonas aeruginosa: Identification of the GlmR Transcriptional Regulator

Tn501 random mutagenesis was applied to the Pseudomonas aeruginosa wild-type strain PAO1 to select for mutants hypersusceptible to aminoglycoside antimicrobial agents. One such mutant, called 19A, was found to be hypersusceptible to a wide range of antibiotics including aminoglycosides, β-lactams, f...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Ramos-Aires, Julio, Plésiat, Patrick, Kocjancic-Curty, Lasta, Köhler, Thilo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982774/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.843-851.2004
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