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Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells

Ire1 is an endoplasmic reticulum (ER) transmembrane protein that senses disturbances in protein folding homeostasis and contributes to a multifaceted response to stress. The nuclease activity of Ire1, in addition to splicing the mRNA encoding the transcription factor Xbp1, mediates mRNA degradation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gaddam, Deepika, Stevens, Nicole, Hollien, Julie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530775/
https://ncbi.nlm.nih.gov/pubmed/23135994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0491
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