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The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation

The exon-junction complex (EJC) deposited on a newly spliced mRNA plays an important role in subsequent mRNA metabolic events. Here we show that an EJC core heterodimer, Y14/Magoh, specifically associates with mRNA-degradation factors, including the mRNA-decapping complex and exoribonucleases, where...

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Autores principales: Chuang, Tzu-Wei, Chang, Wei-Lun, Lee, Kuo-Ming, Tarn, Woan-Yuh
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530774/
https://ncbi.nlm.nih.gov/pubmed/23115303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0217
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