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GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
Estrogen receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcription events that promote tumor growth. Differences in enhancer occupancy by ESR1 contribute to the diverse expression profiles and clinical outcome observed in breas...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530671/ https://ncbi.nlm.nih.gov/pubmed/23172872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.139469.112 |
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