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Regionally Distinct Responses of Microglia and Glial Progenitor Cells to Whole Brain Irradiation in Adult and Aging Rats

Radiation therapy has proven efficacy for treating brain tumors and metastases. Higher doses and larger treatment fields increase the probability of eliminating neoplasms and preventing reoccurrence, but dose and field are limited by damage to normal tissues. Normal tissue injury is greatest during...

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Detalles Bibliográficos
Main Authors: Hua, Kun, Schindler, Matthew K., McQuail, Joseph A., Forbes, M. Elizabeth, Riddle, David R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530502/
https://ncbi.nlm.nih.gov/pubmed/23300752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052728
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