MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D(3) in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells

Hormone antagonist therapy for estrogen receptor positive (ER+) breast cancer patients post radical surgery and radiation therapy has a poor prognosis and also causes bone loss. 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)] is a potent antitumor agent in pre-clinical studies, but caused hypercalcem...

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Bibliographische Detailangaben
Hauptverfasser: Chiang, Kun-Chun, Yeh, Chun-Nan, Chen, Shin-Cheh, Shen, Shih-Che, Hsu, Jun-Te, Yeh, Ta-sen, Pang, Jong-Hwei S., Su, Li-Jen, Takano, Masashi, Kittaka, Atsushi, Juang, Horng-Heng, Chen, Tai C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530235/
https://ncbi.nlm.nih.gov/pubmed/23304196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/310872
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