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MPTP Mouse Models of Parkinson’s Disease: An Update
Among the most widely used models of Parkinson’s disease (PD) are those that employ toxins, especially 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Depending on the protocol used, MPTP yields large variations in nigral cell loss, striatal dopamine loss and behavioral deficits. Motor deficits...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530193/ https://ncbi.nlm.nih.gov/pubmed/23275799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-2011-11023 |
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