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MPTP Mouse Models of Parkinson’s Disease: An Update

Among the most widely used models of Parkinson’s disease (PD) are those that employ toxins, especially 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Depending on the protocol used, MPTP yields large variations in nigral cell loss, striatal dopamine loss and behavioral deficits. Motor deficits...

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Detalhes bibliográficos
Main Authors: Meredith, Gloria E., Rademacher, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530193/
https://ncbi.nlm.nih.gov/pubmed/23275799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-2011-11023
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